Volume 4, Issue 6, December 2016, Page: 256-259
Gibbs Free Energy and Activation Free Energy of Complexation of Some Divalent Cations with Ampicillin in Methanol at Different Temperatures
Elsayed T. Helmy, Marine Pollution Research Lab., National Institute of Oceanography and Fisheries, Ministry of Scientific Research, Alexandria, Egypt; Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt
Esam A. Gomaa, Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt
Elsayed M. Abou Eleef, Basic Science Department, Delta Higher Institute for Engineering & Technology, Dakhlia, Mansoura, Egypt
Received: Sep. 1, 2016;       Accepted: Nov. 8, 2016;       Published: Jan. 21, 2017
DOI: 10.11648/j.ajac.20160406.16      View  2209      Downloads  121
Abstract
The Complexation reaction between Sodium (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (Ampicillin sodium salt) ligand with Ca+2 and Ba+2 ions were studied condctometrically in methanol at four different temperatures (293.15K, 298.15K, 303.15K, 308.15K) On drawing the relation between molar conductance and the ratio of metal to ligand concentrations, different lines are obtained indicating the formation of (1:1 and 2:1 (M:L) stoichiometric complexes. The formation constants, thermodynamic parameters Gibbs free energies and Gibbs free energies of formation of different complexes in methanol were determined.
Keywords
Conductometric Studies, Formation Constant, Gibbs Free Energy, Activation Free Energy, Gibbs Free Energy, Ampicillin, Methanol
To cite this article
Elsayed T. Helmy, Esam A. Gomaa, Elsayed M. Abou Eleef, Gibbs Free Energy and Activation Free Energy of Complexation of Some Divalent Cations with Ampicillin in Methanol at Different Temperatures, American Journal of Applied Chemistry. Vol. 4, No. 6, 2016, pp. 256-259. doi: 10.11648/j.ajac.20160406.16
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Reference
[1]
S. Monica, I. Daniela and M. Ledi, J. Inorg. Biochem., 78, 355, 2000.
[2]
Raja, M. U., Ramesh, R. and Liu, Y. (2011) New Binuclear Pd(II) Thioamide Complexes for the Heck Reaction of Aryl Bromides. Tetrahedron Letters, 52, 5427-5430.
[3]
E. A. Gracia and D. B. Gomis, Mikrochem. Acta. 1996, 124, 179.
[4]
S. Cao and M. J. Zhang, Trace Microprobe Tech., 1999, 17, 157.
[5]
Esam A. Gomaa, Elsayed M. Abou Elleef and E. T. Helmy, RRJPPS | Volume 3 | Issue 3 | July – (2014).
[6]
AHFS DRUG INFORMATION 2006 (2006 ed.). American Society of Health-System Pharmacists. (2006).
[7]
Gryzybkowski, W. and Pastewski, R. (1980) Electrochimica Acta 25, 279.
[8]
Takeda, Y. Bul. Chem. Soc. Jpn 56, 3600. (1983).
[9]
Rahmi-Nasrabadi, M., Ahmedi, F., Pourmor-tazari, S. M., Ganjal, M. R. and Alizadeh, K. (2009) Journal of Molecular Liquids 144, 97.
[10]
E. A. Gomaa, E. M. Abouelleef, E. T. Helmy Reseach and Review J. of Chem. Vol.3, No 2 (2014).
[11]
E. A. Gomaa, E. M. Abouelleef, E. T. Helmy, South. Braz. J. Chem., Vol.21, No. 21, 2013.
[12]
E. A. Gomaa, E. M. Abouelleef, E. T. Helmy, Thermal and Power Engineering, vol. 3, pp. 222-226, 2014.
[13]
Esam A. Gomaa and Elsayed T. Helmy, AASCIT Journal of Nanoscience, Vol. 1, No. 2, (2015).
Browse journals by subject