Kerosene is a liquid mixture of chemicals produced from the distillation of crude oil. It is produced on an industrial scale by distilling crude oil in a process similar to that used to produce diesel or petrol. Kerosene is used as a fuel in cooking stoves and heaters, it also has application as a solvent in paints, cleaners, pesticides and some eye medicines. The study is aimed to determine the ameliorative effect of moringa oleifera leave extract on kerosene induced hematological, serum biochemistry and histological changes in wistar rats. Several households used kerosene stoves as means of cooking which predisposed them to hydrocarbons. Fumes from petroleum products cause environmental pollution, that have resulted into various health challenges. This study has provided information on how kerosene dynamic change in critical values of hematological and serum biochemical indices for clinical applications. It has also provided updated data on leverage of Moringa oleifera in mitigating the damaging effects of kerosene fumes to hematological and serum biochemical indices. An experimental study was conducted and random sampling technique was employed. A total of 20 adult Wister rats were randomly divided into four groups (five each): negative control; exposed to kerosene fume; exposed to kerosene fume later treated with Moringa oleifera and treatment with Moringa only. The results showed polycythemia, hyponatremia, hyperkalemia and hyperchloremia while the histological findings show no tissue damage. In conclusion, kerosene caused hematological and serum biochemical changes and treatment with Moringa oleifera leaf extract showed promising results as observed in this study.
| Published in | American Journal of Applied Chemistry (Volume 9, Issue 6) |
| DOI | 10.11648/j.ajac.20210906.13 |
| Page(s) | 202-206 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Ameliorative Effect, Moringa oleifera, Kerosene, Serum Biochemistry, Hematological, Wistar Rats
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APA Style
Ashiru Dahiru, Abdullahi Ishaq Ja’afaru. (2021). Ameliorative Effect of Moringa oleifera Leave Extract on Kerosene Induced Hematological, Serum Biochemical and Histological Changes in Wistar Rats. American Journal of Applied Chemistry, 9(6), 202-206. https://doi.org/10.11648/j.ajac.20210906.13
ACS Style
Ashiru Dahiru; Abdullahi Ishaq Ja’afaru. Ameliorative Effect of Moringa oleifera Leave Extract on Kerosene Induced Hematological, Serum Biochemical and Histological Changes in Wistar Rats. Am. J. Appl. Chem. 2021, 9(6), 202-206. doi: 10.11648/j.ajac.20210906.13
AMA Style
Ashiru Dahiru, Abdullahi Ishaq Ja’afaru. Ameliorative Effect of Moringa oleifera Leave Extract on Kerosene Induced Hematological, Serum Biochemical and Histological Changes in Wistar Rats. Am J Appl Chem. 2021;9(6):202-206. doi: 10.11648/j.ajac.20210906.13
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Download@article{10.11648/j.ajac.20210906.13,
author = {Ashiru Dahiru and Abdullahi Ishaq Ja’afaru},
title = {Ameliorative Effect of Moringa oleifera Leave Extract on Kerosene Induced Hematological, Serum Biochemical and Histological Changes in Wistar Rats},
journal = {American Journal of Applied Chemistry},
volume = {9},
number = {6},
pages = {202-206},
doi = {10.11648/j.ajac.20210906.13},
url = {https://doi.org/10.11648/j.ajac.20210906.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20210906.13},
abstract = {Kerosene is a liquid mixture of chemicals produced from the distillation of crude oil. It is produced on an industrial scale by distilling crude oil in a process similar to that used to produce diesel or petrol. Kerosene is used as a fuel in cooking stoves and heaters, it also has application as a solvent in paints, cleaners, pesticides and some eye medicines. The study is aimed to determine the ameliorative effect of moringa oleifera leave extract on kerosene induced hematological, serum biochemistry and histological changes in wistar rats. Several households used kerosene stoves as means of cooking which predisposed them to hydrocarbons. Fumes from petroleum products cause environmental pollution, that have resulted into various health challenges. This study has provided information on how kerosene dynamic change in critical values of hematological and serum biochemical indices for clinical applications. It has also provided updated data on leverage of Moringa oleifera in mitigating the damaging effects of kerosene fumes to hematological and serum biochemical indices. An experimental study was conducted and random sampling technique was employed. A total of 20 adult Wister rats were randomly divided into four groups (five each): negative control; exposed to kerosene fume; exposed to kerosene fume later treated with Moringa oleifera and treatment with Moringa only. The results showed polycythemia, hyponatremia, hyperkalemia and hyperchloremia while the histological findings show no tissue damage. In conclusion, kerosene caused hematological and serum biochemical changes and treatment with Moringa oleifera leaf extract showed promising results as observed in this study.},
year = {2021}
}
TY - JOUR T1 - Ameliorative Effect of Moringa oleifera Leave Extract on Kerosene Induced Hematological, Serum Biochemical and Histological Changes in Wistar Rats AU - Ashiru Dahiru AU - Abdullahi Ishaq Ja’afaru Y1 - 2021/12/24 PY - 2021 N1 - https://doi.org/10.11648/j.ajac.20210906.13 DO - 10.11648/j.ajac.20210906.13 T2 - American Journal of Applied Chemistry JF - American Journal of Applied Chemistry JO - American Journal of Applied Chemistry SP - 202 EP - 206 PB - Science Publishing Group SN - 2330-8745 UR - https://doi.org/10.11648/j.ajac.20210906.13 AB - Kerosene is a liquid mixture of chemicals produced from the distillation of crude oil. It is produced on an industrial scale by distilling crude oil in a process similar to that used to produce diesel or petrol. Kerosene is used as a fuel in cooking stoves and heaters, it also has application as a solvent in paints, cleaners, pesticides and some eye medicines. The study is aimed to determine the ameliorative effect of moringa oleifera leave extract on kerosene induced hematological, serum biochemistry and histological changes in wistar rats. Several households used kerosene stoves as means of cooking which predisposed them to hydrocarbons. Fumes from petroleum products cause environmental pollution, that have resulted into various health challenges. This study has provided information on how kerosene dynamic change in critical values of hematological and serum biochemical indices for clinical applications. It has also provided updated data on leverage of Moringa oleifera in mitigating the damaging effects of kerosene fumes to hematological and serum biochemical indices. An experimental study was conducted and random sampling technique was employed. A total of 20 adult Wister rats were randomly divided into four groups (five each): negative control; exposed to kerosene fume; exposed to kerosene fume later treated with Moringa oleifera and treatment with Moringa only. The results showed polycythemia, hyponatremia, hyperkalemia and hyperchloremia while the histological findings show no tissue damage. In conclusion, kerosene caused hematological and serum biochemical changes and treatment with Moringa oleifera leaf extract showed promising results as observed in this study. VL - 9 IS - 6 ER -
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